A very silly concept, but the plot is so intriguing!!
Summary: Shion, a playboy who went around hitting and even fucking every girl he lays his eye on, found himself getting drugged by some girl who was quite upset towards him! She made him drink a very special drug that turned him into a woman everytime he releases his sperm, and turnes him back to a man everytime he receives sperm. Rui, his bestfriend 'helps' him with his predicament, and also helps him search for the drug so he can cure himself. Unfortunately, it isn't quite easy, especially with the challenges and troubles in their path!
Fucked by My Best Friend