General consensus of the readers: wtf
Involves themes of incest, rape, power imbalance, coercion, human experimentation, and intimidation.
Plot was weird and uncomfortable. Ending had a lot of loose ends and no clear conclusion. The sex scenes, for the most part, were well drawn, but since basically all of them were incestuous or rapey, none of them were particularly enjoyable to read. All of the characters were one dimensional and boring (also, very hatable).
My advice to people who have yet to read it:
Read at your own cost.
A Man Who Can't Say No