Wolfgang's Favorite

any non-yaoi (shounen ai is okay) mangas or manhwas that include disabilities and disorders in a respectful and realistic manner that focus specifically on their struggles.
especially looking for disorders like down syndrome, autism (etc.) like http://www.mangago.zone/read-manga/asper_kanojo/ but disabilities like prosthetics, deaf, mute, blind and mental health like depression and suicide are okay as well.