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Going by what was said already in the manga, there is probably some operation that she is going to have done that will basically wipe her memories or something like that. She won't be who she was before. So everything will most likely be fine and he will just try to get her to fall in love with home again. A cliche ending is the most likely to happen, but I'm enjoying reading it, so I will still look forward to continuing!
"My heart hurts" *screech!* "what are you doing?" "Going back to the hospital" I face palmed right there. It's called love dad, most people go through this at least once in their life. Your son is getting to the age where it's very natural to have these feelings. Get over it. He's not sick.