Shoto's waifu's feed

Can y'all give me a recommendation about a story that dealing with a serious real life topic, like it's exist everywhere in real life such as bullying (I have read tons of this), or a story with a character having an illness such as cancer, lupus or whatever chronic Illness it is (I'm not sure if I have read one), or smth like an academic achiever who turns into failure because of the pressure ? Anything will do, thanks in advance !!