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Umm, are you asking for a good anime that isn't yaoi or yuri? I guess Angel Densetsu is pretty good. It's about a very good mannered male student who is misunderstood for a yakuza for his very scary face. One about a girl... maybe Sarasah? It's regular romance, too, but it's about a girl who dies and is taken to a historical place in Japan, but she's a princess. Both are incomplete manga, though, sorry.
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Are sprts anime ok? Then you should watch Yowamushi Pedal, Kuroko no Basket and Haikyuu.
If you like action and misteries, then Psycho-Pass is for you.
Other action + supernatural animes I like are:
Kill la Kill
Owari no Seraph
Noragami
Ao no Exorcist
Tiger & Bunny
Soul Eater
Kyoukai no Kanata
Also, if you want some comedy, then watch those:
Assassination Classroom
Danshi Koukousei no Nichijou
Gugure!! Kokkuri-san
Hetalia
Yondemasu yo Azazel-san (this has really pervy jokes)
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Ano bang gusto mo? mga shoujo? good ones are: bokura no kiseki(reincarnation+high school battle royale), HaruxKiyo (comedy), Dengeki daisy (romcom,drama), iris zero (action+romance)
josei (adult romance): Oishii Kankei (cooking), Midnight Secretary (office+vampire), sekine-kun no koi (slice of life, male main char.)
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I always read devil defense.. so funny but that one is manhwa. It totally worth reading, reall^^
how about black butler?
and mr.Superclean is something that I always read when I am bored.
if you like something sad but you keep reading it try devil with flower.
aand I give my first love to you.
hope you like it^^
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if you like sports anime you can try kuroko no basket and haikyuu
if you like action, supernatural, mystery you can try tokyo ghoul and k project
But please no yaoi I'm not really a fan and also not a girl to girl too..I'm not comfortable with one...Please recommend one that won't dissapoint you...