Responses

it would be funny if his two personalities (or brain halves or whatever) have different sexualities, one is good and the other’s evil... there was a crazy ai murder cult called the zizians that believes something similar & that the different halves are either good or bad or male or female. (not supporting this idea, just the plot seems weak already so it would be exciting)
My hypothesis is that, Hwisoo was aware of his sexual orientation but he couldn't accept it due to some circumstances or traumatic experience perhaps, so he forced himself to be a straight man. And when he decided to get married, that's when his alter ego (Yushin) immerged. It's like Yushin expressing Hwisoo's genuine desires. Then again, this is just a. hypothesis base on what I've read so far.