Responses
It's cause they were poor so they often didn't have nutritious meals and then he couldn't receive proper guiding. His brother tried his best with guiding him through hugs and holding hands but sometimes he needed extensive guiding and you can only get that through sexual contact. So that was off the table. Plus stress & depression, lack of sleep. Everything combined was wearing down his body. But the main issue was guiding.
But damn why his brother looks like an addict? Is his brother have sick, I thought it's just a depression in early chapters and